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Abstract The influences of some factors on the yield of phenylacetic acid in the carbonylation of benzyl
chloride were studied in this paper. These factors included the variety and content of catalyst, and that of
solvent, way of material feeding, reaction temperature, sodium hydrate concentration, triphenylphosphine
content, presence of surfactant, the ratio of organic phase volume to aqueous phase volume etc. The
optimum reaction conditions were found to be: with a one-time pour of 0.15 g Pd(PPh3)2Cl2, 0.24 g
PPh3, 75 ml NaOH of 3.5 mol/L, 20 ml benzyl chloride and 55 ml n-butyl alcohol, and the reaction was
carried out at 50
for about 3 hours. The as-obtained yield of phenylacetic acid was as high as 97.6%.
In addition, the influences of the presence of phenylacetic acid and air in the reaction system were also
studied. The results showed that the presence of air in the system and the entrainment of phenylacetic acid
in the circulating organic phase had great influence on the reaction rate, the stability and performance of
catalyst and the yield of phenylacetic acid. |
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| Keywords：
synthesis
phenylacetic acid
carbonylation
phenyl chloride
dichloro-bistriphenylphosphine
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published: 2005-03-30
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| Cite this article: |
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Zumin Qiu,
Yunbing He,
Dianmo Zheng etc
.Study on the Synthesis of Phenylacetic Acid by Carbonylation of Benzyl Chloride under Normal Pressure[J]
Journal of Natural Gas
, 2005,V14 (1): 40-46
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